Study Title: Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Trial)

Study Setting/Site: The Makerere University Joint AIDS Program (MJAP), Mulago ISS Clinic in Kampala, Uganda

Overview:

This is a five-year project which started with a formative study in year one (November 2018)

Formative study objectives:

1.   To assess the costs (direct and indirect) faced by clients to attend clinic visits

2.   Conduct a pre-implementation assessment of 99DOTS using human-centered design (HCD) principles to refine the delivery strategy

3.   To tailor and pilot test a preliminary decision aid focused on helping clients choose between receiving 3HP via DOT and SAT (via Knowledge, Attitudes and Practices, KAP, Interviews)

Read more …

a) In partnership with the University of California San Francisco (UCSF), MJAP participated in the Test and Treat SEARCH Trial (NCT01864603 with PIs Moses Kamya and Diane Havlir);

b) Client and Provider Perspectives of the Efficiency and Quality of Care in the Context of Rapid Scale-Up of Antiretroviral Therapy;

c) Successful Antiretroviral Therapy Delivery and Retention in Care Among Asymptomatic Individuals with High CD4+ T Cell Counts ≥350 cells/uL in Rural Uganda